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There are over 1,500 citations in Medline relating to the biologic effect of curcumin. Modern science has revealed that curcumin mediates its effects by modulation the expression of important molecular targets involved in cancer, arthritis, diabetes, Crohn’s disease, cardiovascular diseases, osteoporosis, Alzheimer’s disease, psoriasis, and other pathologies.
Curcumin has been shown to block transformation, tumor initiation, tumor promotion, invasion, angiogenesis, and metastasis in a wide variety of tumor cells, including B-cell and T-cell leukaemia, colon carcinoma, epidermoid carcinoma, and various breast carcinoma cells and mammary carcinogenesis.
In vivo, curcumin suppresses carcinogenesis of the skin, stomach, colon, and liver. Curcumin is a potent antioxidant and inhibits lipid peroxidation, oxidation of haemoglobin and various inflammatory diseases.
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